Buy Larocaine Online from Chemicals Pharm Store.
Are you looking to buy Larocaine Online?| is an amazing blend of some of our best-selling research chemicals. Dimethocaine contains Ethyl-Hexedrone and Lidocaine.
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Dimethocaine can only be ordered if you are over 18 years of age.
Please ensure that Dimethocaine is NOT controlled in the country/state to which you wish it to be delivered.
Dimethocaine is not for human consumption.
Buy Larocaine Online / Order Larocaine Wholesale/ Retail Supplies Usage.
In Vivo Use Guide
in rhesus monkeys: When responding was stable, dimethocaine (0.030-1.7 mg/kg/ infusion) was substituted for the cocaine training dose. Dimethocaine administration produced higher response rates compared with that of procaine, and was a more potent reinforcer. Drug effects on behavior were related to DAT occupancy in monkey striatum during neuroimaging with positron emission tomography (PET). DAT occupancy was determined by displacement of 8-(2-[(18)F]fluroethyl)2beta-carbomethoxy-3beta-(4-chlorophenyl)nortropane (FECNT). DAT occupancy was between 66 and 82% and <10-41% for doses of dimethocaine and procaine that maintained maximum response rates, respectively. Acute administration of dimethocaine (10-40 mg/kg, IP) significantly increased locomotor activity and time spent on the drug-paired side and reduced the relative number of entries and time spent on the open arms of the plus-maze in mice.
Route of Administration: Intraperitoneal
High Quality Larocaine Online History .
In Vitro Use Guide
Dimethocaine showed full displacement of [3H]2-beta-carbomethoxy-3-beta-(4-fluorophenyl)tropane 1.5-naphthalenedisulfonate (CFT) binding (0-30 microM tested) and full inhibition of dopamine uptake (0-100 microM tested). Dimethocaine was only slightly less potent than cocaine with an estimated Ki of 1.4 micorM and an IC50 value of 1.2 microM for [3H]CFT binding and dopamine uptake.
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(DMC, larocaine), a synthetic derivative of cocaine, is a widely distributed “legal high” consumed as a “new psychoactive substance” (NPS), originally was used in the 1930s as an anesthetic, primarily in dentistry, ophthalmology, and otolaryngology. This drug completely inhibits dopamine transporter and has had the potential for abuse. Dimethocaine is intended for forensic and research purposes.
DescriptionDimethocaine, also known as DMC or larocaine, is a compound with a stimulatory effect. This effect resembles that of cocaine, although dimethocaine appears to be less potent. Just like cocaine, dimethocaine is addictive due to its stimulation of the reward pathway in the brain. Wikipedia
Molar mass: 278.39 g/mol
ChemSpider ID: 6909
Other names: DMC, larocaine
PubChem CID: 7177
Boiling point: 334 to 403 °C (633 to 757 °F) at 760 mmHg
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