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Buy Prolintane online hydrochloride is a mild central nervous system stimulant that has been marketed in Europe since the 1960s as an antidepressant (i.e. antifatigue) and analeptic1. It is used in neuroscience studies and in research related to CNS stimulants with reduced side effects.
Buy Prolintane Online / Order Prolintane Wholesale / Retail Supplies Usage.
Best place to buy Prolintane online has been used therapeutically in Africa, United State, and Europe and Australia for the treatment of narcolepsy and attention deficit hyperactivity disorder (ADHD), to ameliorate the effects of senile dementia and age-related cognitive decline, and as a tonic to increase motivation and reduce fatigue. Typical adult therapeutic doses of prolintane are 10-40 mg daily.
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Where can i buy Prolintane online ? In therapeutic trials, 20 mg prolintane was found to have a mild stimulant effect equivalent to approximately 100 mg caffeine.2 The use of therapeutic doses of prolintane was associated with a subjective feeling of improved concentration and decreased fatigue.3 In a study of fatigued volunteers, the administration of 20 mg or 40 mg prolintane produced similar, but less intense effects than 20 mg d-amphetamine.4
In experimental studies of healthy volunteers, prolintane had little cardiovascular activity following the administration of a single dose of 20 mg.5 This dose slightly improved performance on some mental tasks. The good safety profile of prolintane was judged to make prolintane suitable for use in elderly people.
In volunteer studies, the administration of 20 mg or 40 mg or prolintane increased wakefulness and improved performance on some perceptual and arithmetic tasks in fatigued individuals.6
The following LD50 values were determined in animal toxicity testing for prolintane:7
mouse LD50 oral 230mg/kg mouse LD50 intraperitoneal 66mg/kg mouse LD50 intravenous 25mg/kg
rat LD50 oral 278mg/kg rat LD50 subcutaneous 142mg/kg rat LD50 intraperitoneal 78mg/kg rat LD50 intravenous 40mg/kg
References: •1. Barceloux DG. “Medical Toxicology of Drug Abuse: Synthesized Chemicals and Psychoactive Plants”. 1st ed. Wiley; 2012: 69-71. •2. McGuinness BW. (1965) “A therapeutic trial of prolintane”. Practitioner 195: 363-365. •3. Newbold GF (1974). “Prolintane in debility and fatigue: report of a trial among college students in Cardiff”. Practitioner 213: 868-870. •4. Hollister, L. E.; Gillespie, H. K. (1970). “A new stimulant, prolintane hydrochloride, compared with dextroamphetamine in fatigued volunteers”. The Journal of Clinical Pharmacology 10 (2): 103–109. doi:10.1177/009127007001000205. PMID 4392006 •5. Kuitunen, T.; Kärkkäinen, S.; Ylitalo, P. (1984). “Comparison of the acute physical and mental effects of ephedrine, fenfluramine, phentermine and prolintane”. Methods and Findings in Experimental and Clinical Pharmacology 6 (5): 265–270. PMID 6471970 •6. Nicholson, A. N.; Stone, B. M.; Jones, M. M. (1980). “Wakefullness and reduced rapid eye movement sleep: Studies with prolintane and pemoline”. British Journal of Clinical Pharmacology 10 (5): 465–472. PMC 1430138. PMID 7437258 •7. Oyo Yakuri. Pharmacometrics. Vol. 9, Pg. 601, 1975.
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