Ambien (Zolpidem) Tablets
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Zolpidem,which usually sold under the brand name Ambien is a short acting sedative that is frequently used to treat sleep problems (insomnia) in adults. Ambien is also found to be effective as an anticonvulsant but with limited use. It is widely prescribed as a short term hypnotic meaning the regular tablet will initiate the sleep without maintaining it. Simply put, if you have trouble falling asleepAmbien will do the trick.Ambien belongs to a group of drugs called sedative-hypnotics and works by activating the neurotransmitter GABA and helping it bind to the receptors. This increased GABA activity, in turn, hampers‘insomnia causing’ nervous firings. So the reduced neuronal firing elicits a calming and a soothing effect resulting in induction of sleep. Recently an extended release tablet(Ambien CR ) also has been introduced which will not only start the sleep but will also maintain it.
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It is important to take Ambien exactly as prescribed by the doctor. The usual dosage forms are 5mg and 10mg tablets. Now a 12.5mg extended release tablet (Ambien CR ) is also available in the market. It is wise to start with thelowest dose which is 5mg (in women), and 5mg or 10mg (in men) at bedtime. If you think the5mg dose is less effective the doctor might up the dosage up to 10mg per day. The desired effect can get delayed if taken with a heavy meal. Geriatric people must take the minimum dose with a sufficient monitoring.
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As sleep disturbances may be the ‘presenting symptom’ of an underlying physical and/or psychiatric disorder, it is wise to start Ambien after a thorough medical evaluation. Just because we control one symptom it does not mean the deep lying disease is also controlled. However in most cases, an exact cause for insomnia is not found, yet Ambien is prescribed.
If you have a history of allergy to any kind of sedative it is wise to mention it to the healthcare provider. Features of allergy include nausea (urge to vomit), vomiting, difficulty in breathing, rashes etc. Patients with GERD (gastro esophageal reflux disease) or simply ‘acid reflux’ should not take Ambien as they can get significantly higher esophageal (food pipe) exposure to gastric acid,increasing the risk of cancer.
Just like other sedative/hypnotic drugs, Ambien should be administered with caution to those who are suffering from depression due to their suicidal tendencies which can result in an intentional over dosage. Therefore the minimum dose of the drug (5mg/day) is recommended for them.
Ambien is in the Pregnancy category C meaning that it is not recommended for childbearing mothers. Several tests using rabbits and rats have shown that taking Ambien can pose a number of potential risks to the developing fetus. Although not contraindicated for breastfeeding mothers, it is wise to ask the doctor before starting.
Ambien has a very good safety profile and has relatively fewer side effects compared to many sedatives. Trivial side effects include dizziness, daytime sleepiness, nausea, and diarrhea. With long time use, you can get back pains, chest pains, palpitations, abdominal pains, constipation,and sinusitis, which should be told to the healthcare provider promptly. Several users have also reported bouts of unexplained sleepwalking.
Using another sedative or alcohol along with Ambien is not recommended as it can lead to severe central nervous system (CNS) depression in which there can be lack of coordination, slowed or slurred speech, poor judgment, slowed breathing and slowed heart rate, which can be alarming.
Although it is frequently prescribed as asedative, a number of studies suggested that Ambien might have a better anticonvulsant potency than previously thought. A recent study done by Laboratory for Molecular Neuropharmacology, Division of Molecular Medicine, Ruder Boscov Institute suggeststhat in addition to strong sedative activity Ambien has potent anticonvulsant properties, although this is not an approved use,as the dosage needed for preventing seizures is 20 times the sedating dose.
According to the National Sleep Foundation (NSF), millions of individuals do not get adequate sleep and many suffer from a condition called ‘Insomnia’ notorious for making us unable to sleep. Zolpidem, the active ingredient in Ambien is in use for insomnia since 1988. Ambien is effective in reducing the time to sleep onset and increasing the total sleep time as evident by numerous studies. The hypnotic effects ofAmbien is usually high for the first three hours post-dose gradually declining after that with the ordinary tablet. However,the extended release tablets provide‘layered sustained release’ maintaining a constant sleep throughout.
Can You Order Ambien Online?Yes, you can but Ambien is a scheduled drug in most countries which will make it illegal. However, since the law enforcement has far bigger fish to fry than someone importing a relatively small amount of Schedule III or IV pills for personal consumption, they won’t pursue the matter even if your package is discovered. Nonetheless the ‘Food and Drug Administration’ wants to warn consumers about the possible dangers of buying medicines over the Internet as sedatives can lead to dependency which can be detrimental to the body in the long run.
It is also crucial to choose a legit trustworthy online pharmacy as the market is flooded with counterfeit drugs that may look exactly like real FDA-approved medicines. But as usual, the online prices of Ambien can be far cheaper than getting your prescription filled at the local drug store.
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