Dextromethorphan
Medication

Description

Dextromethorphan is a medication most often used as a cough suppressant in over-the-counter cold and cough medicines. It is sold in syrup, tablet, spray, and lozenge forms.
Molar mass: 271.4 g/mol
Elimination half-life: 2–4 hours (extensive metabolizers); 24 hours (poor metabolizers)
Metabolism: Hepatic (liver) enzymes: major CYP2D6, minor CYP3A4, and minor CYP3A5
Formula: C18H25NO
ATC code: R05DA09 (WHO)
Melting point: 111 °C (232 °F)
Bioavailability: 11%
Does DXM help with anxiety?
Neurogenesis in the hippocampus was suppressed by DXM treatment, which was indicated by decreases in number of proliferative cells and doublecortin (an immature neuron marker)-positive new neurons. ... These findings suggest that DXM induces depression- and anxiety-like behavior and suppresses neurogenesis in rats.