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Ibuprofen Medication Description DescriptionIbuprofen is a medication in the nonsteroidal anti-inflammatory drug class that is used for treating pain, fever, and inflammation. This includes painful menstrual periods, migraines, and rheumatoid arthritis. It may also be used to close a patent ductus arteriosus in a premature baby. Formula: C13H18O2 Onset of action: 30 min Other names: isobutylphenylpropionic acid Elimination half-life: 2–4 h Solubility in water: 0.021 mg/mL (20 °C) Metabolism: Liver (CYP2C9) Melting point: 75 to 78 °C (167 to 172 °F)