7-Hydroxymitragynine
Description
Description7-Hydroxymitragynine is a terpenoid indole alkaloid from the plant Mitragyna speciosa, commonly known as Kratom.
Formula: C23H30N2O5
ChemSpider ID: 23152144
Acidity (pKa): 12.203
Basicity (pKb): 1.794
PubChem CID: 44301524
Molar mass: 414.502 g·mol−1
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Kratom (7-Hydroxymitragynine) Powder
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Description
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Both mitragynine and 7-hydroxymitragynine act on mu-opioid receptors in the same way as heroin or oxycodone. Kratom additionally acts on many other receptors, including alpha-2 receptors, GABA receptors, serotonin receptors, and noradrenergic receptors.
Mitragynine. Mitragynine is an indole-based alkaloid and the most abundant active alkaloid in the Southeast Asian plant Mitragyna speciosa, commonly known as kratom. The total alkaloid concentration in dried leaves ranges from 0.5 to 1.5 %.
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Mitragynine and 7-hydroxymitragynine, the two alkaloids mainly responsible for the effects of kratom, are selective and full agonists of the μ-subtype opioid receptor (MOR). The receptor agonist effect of kratom alkaloids is antagonised by the opioid receptor antagonist naloxone. … Kratom is slightly toxic to animals.
Even though kratom reacts to the opioid receptors, it only binds temporary so it does not produce a long-term dependency. However, if you take kratom daily, your tolerance will increase over time. It is highly recommended to start with a low dose and to only increase the dosage if absolutely necessary.
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Liver and Kidney Damage: When used for a long time in high doses, the liver and kidney will become significantly damaged. … They can become overworked, which can lead to kidney failure among people with liver damage. Negative Interactions: Mixing Kratom with other drugs can cause potentially hazardous side-effects.
Table 2
| Brand name | Concentration | |
|---|---|---|
| Mitragynine | 7-Hydroxymitragynine | |
| Phoriatm Borneo red vein | 14.9 μg/mg | 346.2 ng/mg |
| Phoriatm maeng da kava | 10.9 μg/mg | 300.8 ng/mg |
| Phoriatm maeng da blue lotus | 9.7 μg/mg | 146.7 ng/mg |
Another very important note is that, just like any other tea, the longer you boil it or let it steep, the stronger the flavor and effect. Kratom is bitter, and the taste continues to deepen the longer it has been submerged in hot water.
Additional information
| Price | 100g, 1kg, 50g |
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